Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DHX15DEAH-box helicase 15. (795 aa)    
Predicted Functional Partners:
TFIP11
Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...]
   
 0.999
SF3B3
Splicing factor 3b subunit 3.
   
 0.999
SF3B1
Splicing factor 3b subunit 1.
   
 0.998
CHERP
Calcium homeostasis endoplasmic reticulum protein.
   
 0.998
SNRPA1
Small nuclear ribonucleoprotein polypeptide A.
   
 0.998
SF3B4
Splicing factor 3b subunit 4.
   
 0.997
SF3A3
Splicing factor 3a subunit 3.
   
 0.996
PHF5A
PHD finger protein 5A.
   
 0.996
CDC40
Cell division cycle 40.
   
 0.995
SYF2
SYF2 pre-mRNA splicing factor.
    
 0.995
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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