STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIF3L1NIF3-like protein 1; May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation. (377 aa)    
Predicted Functional Partners:
GCH1
GTP cyclohydrolase 1.
    
 0.859
PTS
6-pyruvoyl tetrahydrobiopterin synthase.
    
 0.816
GPN1
GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
   
    0.797
HDDC3
HD domain containing 3.
  
 
  0.768
PRPF40A
Pre-mRNA processing factor 40 homolog A.
  
  
 0.763
G1Q3N4_MYOLU
Elp3 domain-containing protein.
    
  0.754
KLHL30
Kelch like family member 30.
      
 0.749
LOC102436663
Aminotran_1_2 domain-containing protein.
  
    0.749
PKLR
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.741
TGDS
TDP-glucose 4,6-dehydratase.
  
    0.739
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.