Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
NGLY1N-glycanase 1. (614 aa)    
Predicted Functional Partners:
RAD23B
RAD23 homolog B, nucleotide excision repair protein.
    
 0.998
RAD23A
RAD23 homolog A, nucleotide excision repair protein.
    
 0.993
VCP
Valosin containing protein; Belongs to the AAA ATPase family.
    
 0.992
PSMC1
Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family.
   
 0.987
AMFR
Autocrine motility factor receptor.
   
 0.986
DERL1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 0.974
UBXN1
UBX domain protein 1.
    
 0.968
UBXN2B
UBX domain protein 2B.
    
 
 0.960
KATNAL2
Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
    
 0.932
SYVN1
Synoviolin 1.
   
 0.925
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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