Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LETM2Leucine zipper and EF-hand containing transmembrane protein 2. (480 aa)    
Predicted Functional Partners:
FAM118A
Family with sequence similarity 118 member A.
    
 
 0.813
LOC102440281
Uncharacterized protein.
    
   0.771
EIF3J
Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]
    
 
 0.754
DNAJC18
DnaJ heat shock protein family (Hsp40) member C18.
   
 
 0.735
UQCRC1
Ubiquinol-cytochrome c reductase core protein 1.
   
 0.725
LOC102436561
Uncharacterized protein; Belongs to the peptidase M16 family.
   
 0.725
G1PC85_MYOLU
Uncharacterized protein; Belongs to the peptidase M16 family.
   
 0.725
TMEM39B
Transmembrane protein 39B.
      
 0.714
RPL8
Ribosomal protein L8.
    
 
 0.704
RAB11FIP1
RAB11 family interacting protein 1.
    
 
 0.700
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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