STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (621 aa)    
Predicted Functional Partners:
PRL
Prolactin.
    
 0.998
JAK2
Tyrosine-protein kinase.
    
 0.991
LOC102442251
Uncharacterized protein.
   
 0.979
LEP
Leptin.
     
 0.969
JAK3
Tyrosine-protein kinase.
    
 0.940
G1NSK2_MYOLU
GHBP domain-containing protein.
     
0.934
ENSMLUP00000022305
annotation not available
     
 0.934
JAK1
Tyrosine-protein kinase.
    
 0.927
TYK2
Tyrosine-protein kinase.
    
 0.927
CISH
Cytokine inducible SH2 containing protein.
    
 0.908
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.