STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G1NWC3_MYOLUUncharacterized protein. (683 aa)    
Predicted Functional Partners:
G1PBB6_MYOLU
Uncharacterized protein.
    
  0.763
GTF3C3
General transcription factor IIIC subunit 3.
    
 0.638
ARID4B
AT-rich interaction domain 4B.
    
 0.634
G1PZQ6_MYOLU
Uncharacterized protein.
    
  0.627
MRPS12
Mitochondrial ribosomal protein S12; Belongs to the universal ribosomal protein uS12 family.
    
 0.624
G1PHV0_MYOLU
FAT domain-containing protein.
   
 0.622
G1QG66_MYOLU
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.622
MRPS10
Mitochondrial ribosomal protein S10.
   
  0.585
CHCHD1
Coiled-coil-helix-coiled-coil-helix domain containing 1.
   
  0.581
SUFU
Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...]
   
 0.580
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.