Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDC40Cell division cycle 40. (578 aa)    
Predicted Functional Partners:
SYF2
SYF2 pre-mRNA splicing factor.
    
 0.998
PRPF18
SFM domain-containing protein.
   
 0.998
DHX38
DEAH-box helicase 38.
   
 0.998
SLU7
SLU7 homolog, splicing factor.
   
 0.997
CCDC12
Coiled-coil domain containing 12.
    
  0.996
DHX15
DEAH-box helicase 15.
   
 0.995
TFIP11
Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...]
    
 0.995
DHX16
DEAH-box helicase 16.
   
 0.995
CWF19L2
CWF19 like cell cycle control factor 2.
   
 0.995
YJU2
YJU2 splicing factor homolog.
   
 0.995
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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