ATIC protein (Myotis lucifugus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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proteins of unknown 3D structure

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Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADSL	ADSS2	ENSMLUP00000016831	ENSMLUP00000015792	Adenylosuccinate lyase.	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.999
ADSL	ATIC	ENSMLUP00000016831	ENSMLUP00000001670	Adenylosuccinate lyase.	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	0.999
ADSL	GART	ENSMLUP00000016831	ENSMLUP00000011297	Adenylosuccinate lyase.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.999
ADSL	GMPR	ENSMLUP00000016831	ENSMLUP00000000811	Adenylosuccinate lyase.	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	0.843
ADSL	IMPDH1	ENSMLUP00000016831	ENSMLUP00000002006	Adenylosuccinate lyase.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	0.898
ADSL	IMPDH2	ENSMLUP00000016831	ENSMLUP00000012712	Adenylosuccinate lyase.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	0.899
ADSL	MTHFD1	ENSMLUP00000016831	ENSMLUP00000015079	Adenylosuccinate lyase.	Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1.	0.622
ADSL	MTHFD1L	ENSMLUP00000016831	ENSMLUP00000004836	Adenylosuccinate lyase.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.	0.622
ADSL	PAICS	ENSMLUP00000016831	ENSMLUP00000016921	Adenylosuccinate lyase.	AIRC domain-containing protein.	0.999
ADSL	PPAT	ENSMLUP00000016831	ENSMLUP00000006658	Adenylosuccinate lyase.	Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.993
ADSS2	ADSL	ENSMLUP00000015792	ENSMLUP00000016831	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Adenylosuccinate lyase.	0.999
ADSS2	ATIC	ENSMLUP00000015792	ENSMLUP00000001670	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	0.998
ADSS2	GART	ENSMLUP00000015792	ENSMLUP00000011297	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.998
ADSS2	GMPR	ENSMLUP00000015792	ENSMLUP00000000811	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	0.989
ADSS2	IMPDH1	ENSMLUP00000015792	ENSMLUP00000002006	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	0.990
ADSS2	IMPDH2	ENSMLUP00000015792	ENSMLUP00000012712	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	0.989
ADSS2	PAICS	ENSMLUP00000015792	ENSMLUP00000016921	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	AIRC domain-containing protein.	0.984
ADSS2	PPAT	ENSMLUP00000015792	ENSMLUP00000006658	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.886
ATIC	ADSL	ENSMLUP00000001670	ENSMLUP00000016831	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	Adenylosuccinate lyase.	0.999
ATIC	ADSS2	ENSMLUP00000001670	ENSMLUP00000015792	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.998