Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TBRG1Transforming growth factor beta regulator 1. (394 aa)    
Predicted Functional Partners:
KDM6A
Lysine demethylase 6A.
   
 0.877
KDM6B
Lysine demethylase 6B.
   
 0.877
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
    
 0.873
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
    
 0.859
LOC106698231
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.774
ENSMLUP00000017704
annotation not available
    
 0.774
ENSMLUP00000020187
annotation not available
    
 0.774
LOC102424579
annotation not available
    
 0.774
ENSMLUP00000022553
annotation not available
    
 0.774
COPS2
COP9 signalosome subunit 2.
   
  
 0.760
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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