S100A4 protein (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

S100A4

Protein S100; Belongs to the S-100 family. (101 aa)

Predicted Functional Partners:

G1P5B5_MYOLU

0.963

ANXA2

0.934

G1QDT1_MYOLU

0.934

LOC102434939

0.916

S100B

0.916

S100A14

0.915

TP53

0.904

G1PZ51_MYOLU

0.904

G1Q8T5_MYOLU

0.904

ANXA1

0.903

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANXA1	ANXA2	ENSMLUP00000000430	ENSMLUP00000002240	Annexin.	Annexin.	0.990
ANXA1	G1P5B5_MYOLU	ENSMLUP00000000430	ENSMLUP00000005193	Annexin.	Uncharacterized protein.	0.913
ANXA1	G1PZ51_MYOLU	ENSMLUP00000000430	ENSMLUP00000016733	Annexin.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.736
ANXA1	G1Q8T5_MYOLU	ENSMLUP00000000430	ENSMLUP00000020118	Annexin.	Uncharacterized protein.	0.736
ANXA1	G1QDT1_MYOLU	ENSMLUP00000000430	ENSMLUP00000021864	Annexin.	Annexin.	0.990
ANXA1	S100A4	ENSMLUP00000000430	ENSMLUP00000001740	Annexin.	Protein S100; Belongs to the S-100 family.	0.903
ANXA1	TP53	ENSMLUP00000000430	ENSMLUP00000005861	Annexin.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.736
ANXA2	ANXA1	ENSMLUP00000002240	ENSMLUP00000000430	Annexin.	Annexin.	0.990
ANXA2	G1P5B5_MYOLU	ENSMLUP00000002240	ENSMLUP00000005193	Annexin.	Uncharacterized protein.	0.816
ANXA2	G1PZ51_MYOLU	ENSMLUP00000002240	ENSMLUP00000016733	Annexin.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.442
ANXA2	G1Q8T5_MYOLU	ENSMLUP00000002240	ENSMLUP00000020118	Annexin.	Uncharacterized protein.	0.442
ANXA2	S100A4	ENSMLUP00000002240	ENSMLUP00000001740	Annexin.	Protein S100; Belongs to the S-100 family.	0.934
ANXA2	TP53	ENSMLUP00000002240	ENSMLUP00000005861	Annexin.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.442
G1P5B5_MYOLU	ANXA1	ENSMLUP00000005193	ENSMLUP00000000430	Uncharacterized protein.	Annexin.	0.913
G1P5B5_MYOLU	ANXA2	ENSMLUP00000005193	ENSMLUP00000002240	Uncharacterized protein.	Annexin.	0.816
G1P5B5_MYOLU	G1PZ51_MYOLU	ENSMLUP00000005193	ENSMLUP00000016733	Uncharacterized protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.839
G1P5B5_MYOLU	G1Q8T5_MYOLU	ENSMLUP00000005193	ENSMLUP00000020118	Uncharacterized protein.	Uncharacterized protein.	0.839
G1P5B5_MYOLU	G1QDT1_MYOLU	ENSMLUP00000005193	ENSMLUP00000021864	Uncharacterized protein.	Annexin.	0.816
G1P5B5_MYOLU	S100A4	ENSMLUP00000005193	ENSMLUP00000001740	Uncharacterized protein.	Protein S100; Belongs to the S-100 family.	0.963
G1P5B5_MYOLU	TP53	ENSMLUP00000005193	ENSMLUP00000005861	Uncharacterized protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.839