RUNDC3A protein (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

RUNDC3A

RUN domain containing 3A. (446 aa)

Predicted Functional Partners:

BMP2K

0.957

AAK1

0.957

ITSN1

0.953

EPS15L1

0.949

AP2A2

0.946

REPS1

0.943

AP2M1

0.927

LOC102442363

0.918

ENSMLUP00000021598

0.918

AP1B1

0.916

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAK1	AP1B1	ENSMLUP00000008301	ENSMLUP00000011041	AP2 associated kinase 1.	AP complex subunit beta.	0.929
AAK1	AP2A2	ENSMLUP00000008301	ENSMLUP00000014301	AP2 associated kinase 1.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.918
AAK1	AP2M1	ENSMLUP00000008301	ENSMLUP00000012326	AP2 associated kinase 1.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.993
AAK1	ENSMLUP00000021598	ENSMLUP00000008301	ENSMLUP00000021598	AP2 associated kinase 1.	annotation not available	0.963
AAK1	EPS15L1	ENSMLUP00000008301	ENSMLUP00000000543	AP2 associated kinase 1.	Epidermal growth factor receptor pathway substrate 15 like 1.	0.947
AAK1	ITSN1	ENSMLUP00000008301	ENSMLUP00000016474	AP2 associated kinase 1.	Intersectin 1.	0.720
AAK1	LOC102442363	ENSMLUP00000008301	ENSMLUP00000016456	AP2 associated kinase 1.	Clat_adaptor_s domain-containing protein.	0.963
AAK1	REPS1	ENSMLUP00000008301	ENSMLUP00000003313	AP2 associated kinase 1.	RALBP1 associated Eps domain containing 1.	0.997
AAK1	RUNDC3A	ENSMLUP00000008301	ENSMLUP00000001748	AP2 associated kinase 1.	RUN domain containing 3A.	0.957
AP1B1	AAK1	ENSMLUP00000011041	ENSMLUP00000008301	AP complex subunit beta.	AP2 associated kinase 1.	0.929
AP1B1	AP2A2	ENSMLUP00000011041	ENSMLUP00000014301	AP complex subunit beta.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.998
AP1B1	AP2M1	ENSMLUP00000011041	ENSMLUP00000012326	AP complex subunit beta.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.995
AP1B1	BMP2K	ENSMLUP00000011041	ENSMLUP00000008177	AP complex subunit beta.	BMP2 inducible kinase.	0.867
AP1B1	ENSMLUP00000021598	ENSMLUP00000011041	ENSMLUP00000021598	AP complex subunit beta.	annotation not available	0.983
AP1B1	EPS15L1	ENSMLUP00000011041	ENSMLUP00000000543	AP complex subunit beta.	Epidermal growth factor receptor pathway substrate 15 like 1.	0.908
AP1B1	ITSN1	ENSMLUP00000011041	ENSMLUP00000016474	AP complex subunit beta.	Intersectin 1.	0.949
AP1B1	LOC102442363	ENSMLUP00000011041	ENSMLUP00000016456	AP complex subunit beta.	Clat_adaptor_s domain-containing protein.	0.983
AP1B1	REPS1	ENSMLUP00000011041	ENSMLUP00000003313	AP complex subunit beta.	RALBP1 associated Eps domain containing 1.	0.878
AP1B1	RUNDC3A	ENSMLUP00000011041	ENSMLUP00000001748	AP complex subunit beta.	RUN domain containing 3A.	0.916
AP2A2	AAK1	ENSMLUP00000014301	ENSMLUP00000008301	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	AP2 associated kinase 1.	0.918