STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRNGranulin precursor. (597 aa)    
Predicted Functional Partners:
CTSZ
Cathepsin Z; Belongs to the peptidase C1 family.
   
 0.919
CS
Citrate synthase; Belongs to the citrate synthase family.
   
   0.910
DRG1
Developmentally regulated GTP binding protein 1.
    
   0.906
C15orf40
Uncharacterized protein.
    
   0.906
POLE2
DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.
    
   0.906
SLC25A1
Solute carrier family 25 member 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.
    
   0.906
CTSB
Cathepsin B; Belongs to the peptidase C1 family.
   
 0.875
SORT1
Sortilin.
    
 
 0.852
CTSF
Cathepsin F; Belongs to the peptidase C1 family.
   
 0.851
CTSS
Cathepsin S; Belongs to the peptidase C1 family.
   
 0.821
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.