Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GRNGranulin precursor. (597 aa)    
Predicted Functional Partners:
SORT1
Sortilin.
    
 
 0.977
CD68
Uncharacterized protein.
   
 
 0.927
PSAP
Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.
   
 0.887
CTSB
Cathepsin B; Belongs to the peptidase C1 family.
   
 0.878
CCNT1
Cyclin T1; Belongs to the cyclin family.
    
 
 0.830
DNAJC10
DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.
    
 
 0.826
G1PXQ4_MYOLU
Uncharacterized protein.
    
 
 0.820
GLRX3
Uncharacterized protein.
    
 
 0.820
HSPG2
Heparan sulfate proteoglycan 2.
    
 
 0.805
BAP1
Ubiquitin carboxyl-terminal hydrolase.
    
   0.795
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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