STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NSMCE3NSE3 homolog, SMC5-SMC6 complex component. (300 aa)    
Predicted Functional Partners:
NSMCE4A
Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
   
 0.972
NSMCE1
NSE1 homolog, SMC5-SMC6 complex component.
   
 0.971
NSMCE2
NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase.
    
 0.958
SMC6
Structural maintenance of chromosomes 6.
   
 0.952
SMC5
Structural maintenance of chromosomes 5.
   
 0.946
EID1
EP300 interacting inhibitor of differentiation 1.
    
 
 0.772
SMC3
Structural maintenance of chromosomes protein.
    
 0.710
UBE2I
Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.662
SMC1A
Structural maintenance of chromosomes protein.
   
 0.650
SMC1B
Structural maintenance of chromosomes protein.
   
 0.650
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.