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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FGD2FYVE, RhoGEF and PH domain containing 2. (644 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
    
 0.744
TCF19
Transcription factor 19.
      
 0.690
RHOU
Ras homolog family member U.
    
 0.665
ARHGEF1
Rho guanine nucleotide exchange factor 1.
    
0.624
ANKLE1
Ankyrin repeat and LEM domain containing 1.
      
 0.607
G1Q0T5_MYOLU
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
   
  
 0.597
RAC1
Rac family small GTPase 1.
   
 0.575
KCNT2
Potassium sodium-activated channel subfamily T member 2.
      
 0.572
LRP8
LDL receptor related protein 8.
      
 0.571
RAC2
Rac family small GTPase 2.
   
 0.558
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.