STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSPG2Heparan sulfate proteoglycan 2. (3509 aa)    
Predicted Functional Partners:
DAG1
Dystroglycan 1.
   
 0.975
NID1
Nidogen 1.
   
 0.969
G1Q1H6_MYOLU
NIDO domain-containing protein.
   
 0.969
NID2
Nidogen 2.
   
 0.934
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
     
 0.914
ITGA2
Integrin subunit alpha 2; Belongs to the integrin alpha chain family.
    
 0.904
VEGFA
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
    
 0.885
G1PG84_MYOLU
Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
   
 0.840
EGF
Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
    
 0.817
DCN
Decorin; May affect the rate of fibrils formation.
   
 
 0.812
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.