Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HSPG2Heparan sulfate proteoglycan 2. (3509 aa)    
Predicted Functional Partners:
DAG1
Dystroglycan 1.
   
 0.985
NID1
Nidogen 1.
   
 0.980
G1Q1H6_MYOLU
NIDO domain-containing protein.
   
 0.980
NID2
Nidogen 2.
   
 0.969
MUSK
Muscle associated receptor tyrosine kinase.
    
 0.939
FBLN2
Fibulin 2.
   
 0.932
TINAG
Tubulointerstitial nephritis antigen; Belongs to the peptidase C1 family.
   
 
 0.926
LAMA1
Laminin subunit alpha 1.
   
 0.874
G1PG84_MYOLU
Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
   
 0.844
FBLN1
Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
   
 0.824
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
Server load: low (16%) [HD]