STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SASS6SAS-6 centriolar assembly protein. (656 aa)    
Predicted Functional Partners:
WRN
WRN RecQ like helicase.
   
 0.991
FANCM
FA complementation group M.
   
 0.991
CENPJ
Centromere protein J.
   
 0.967
STIL
STIL centriolar assembly protein.
   
 0.964
RPA3
Replication protein A3.
   
 0.957
MEIOB
Meiosis specific with OB-fold.
   
 0.948
RPA1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
   
 0.948
RAD52
RAD52 homolog, DNA repair protein.
    
 0.943
ATR
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
   
 0.938
PRIM1
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
   
 0.922
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.