Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
F8Coagulation factor VIII; Belongs to the multicopper oxidase family. (2331 aa)    
Predicted Functional Partners:
VWF
Von Willebrand factor.
    
 0.999
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.986
PROS1
Protein S.
   
 0.978
G1PLV6_MYOLU
Uncharacterized protein.
    
 0.971
F7
Coagulation factor VII.
   
 0.952
L7N1Q3_MYOLU
Uncharacterized protein.
   
 0.935
G1Q5N3_MYOLU
Uncharacterized protein.
   
 0.935
G1QAT0_MYOLU
Uncharacterized protein; Belongs to the peptidase S1 family.
   
 0.935
LMAN1
Lectin, mannose binding 1.
    
 0.920
F9
Coagulation factor IX.
   
 0.916
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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