Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)    
Predicted Functional Partners:
OPRM1
Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family.
    
  0.990
GNAS
GNAS complex locus.
    
 0.989
G1PJN7_MYOLU
Uncharacterized protein.
    
 0.989
CALCR
Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.
    
  0.988
DRD2
Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.
    
 0.986
ADCY5
Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
    
 0.982
GPER1
G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
  0.982
AVPR2
Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
    
  0.981
DRD3
Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.
    
 0.979
GNB1
G protein subunit beta 1.
   
 0.978
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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