STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C16orf74Chromosome 16 open reading frame 74. (75 aa)    
Predicted Functional Partners:
EMC1
ER membrane protein complex subunit 1.
    
 
 0.957
EMC2
ER membrane protein complex subunit 2.
   
 
 0.934
EMC3
ER membrane protein complex subunit 3; Belongs to the EMC3 family.
    
 
 0.892
EMC4
ER membrane protein complex subunit 4.
   
 
 0.890
EMC6
ER membrane protein complex subunit 6.
   
 
 0.839
EMC7
ER membrane protein complex subunit 7.
    
 
 0.823
PPP3CA
Serine/threonine-protein phosphatase.
    
 
 0.707
TNS4
Tensin 4.
      
 0.641
UNC119
Unc-119 lipid binding chaperone.
    
   0.613
ADORA2B
Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.
      
 0.607
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.