Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ITIH5Inter-alpha-trypsin inhibitor heavy chain 5. (941 aa)    
Predicted Functional Partners:
TRAF7
TNF receptor associated factor 7.
   
 0.731
RASAL3
RAS protein activator like 3.
    
 0.726
CLEC3B
C-type lectin domain family 3 member B.
   
 0.717
LOC102442976
Uncharacterized protein.
    
 0.706
CDC37
Cell division cycle 37.
    
 0.698
NBR1
NBR1 autophagy cargo receptor.
    
 0.690
PELI1
E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
    
 0.684
PELI3
E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
    
 0.684
PELI2
Pellino E3 ubiquitin protein ligase family member 2.
    
 0.684
VTN
SMB domain-containing protein.
   
  0.674
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
Server load: low (28%) [HD]