STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM92AUncharacterized protein. (288 aa)    
Predicted Functional Partners:
ADGRB3
Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family.
    
 0.818
ADGRB2
Adhesion G protein-coupled receptor B2; Belongs to the G-protein coupled receptor 2 family.
    
 0.818
RANBP2
RAN binding protein 2.
   
 0.764
RNF8
E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]
   
  0.700
G1NTP5_MYOLU
Uncharacterized protein.
    
 0.682
ZFAND4
Zinc finger AN1-type containing 4.
    
 0.675
NEK6
NIMA related kinase 6; Belongs to the protein kinase superfamily.
    
 0.675
NEK7
NIMA related kinase 7; Belongs to the protein kinase superfamily.
    
 0.675
DPH3
Diphthamide biosynthesis 3.
    
 
 0.652
RBPJL
Recombination signal binding protein for immunoglobulin kappa J region like.
   
 0.645
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.