Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
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Co-expression
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[Homology]
Score
MDH1Malate dehydrogenase. (352 aa)    
Predicted Functional Partners:
CS
Citrate synthase; Belongs to the citrate synthase family.
  
 0.996
MDH2
Malate dehydrogenase.
   
 0.991
FH
Uncharacterized protein.
  
 0.990
GOT1
Aspartate aminotransferase.
   
 0.990
LOC102425029
Lyase_1 domain-containing protein.
  
 0.990
GOT2
Aspartate aminotransferase.
   
 0.989
PC
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 0.984
ACLY
ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.
  
 0.982
GOT1L1
Glutamic-oxaloacetic transaminase 1 like 1.
   
 0.980
ME3
Malic enzyme.
  
 0.977
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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