STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITGB5Integrin beta; Belongs to the integrin beta chain family. (778 aa)    
Predicted Functional Partners:
PAK4
Non-specific serine/threonine protein kinase.
    
 0.999
ITGAV
Integrin subunit alpha V; Belongs to the integrin alpha chain family.
   
 0.998
TLN2
Talin 2.
   
 0.992
TLN1
Talin 1.
   
 0.992
G1PKI8_MYOLU
VWFA domain-containing protein.
   
 0.991
VCL
Vinculin.
   
 0.988
PXN
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
   
 0.988
FN1
Fibronectin 1.
    
 0.987
FLNA
Filamin A.
    
 0.984
ITGA5
Integrin subunit alpha 5; Belongs to the integrin alpha chain family.
   
 0.982
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.