STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHC1SHC adaptor protein 1. (584 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
   
 0.998
G1P5B5_MYOLU
Uncharacterized protein.
    
 0.995
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
    
 0.992
PTPN12
Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.
    
 0.988
PTPN11
Protein tyrosine phosphatase non-receptor type 11.
   
 0.981
ERBB3
Erb-b2 receptor tyrosine kinase 3.
    
 0.979
ERBB2
Receptor protein-tyrosine kinase.
    
 0.979
SRC
Tyrosine-protein kinase.
   
0.979
NTRK3
Tyrosine-protein kinase receptor.
   
 0.977
TEK
TEK receptor tyrosine kinase.
   
 0.972
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.