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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DONSONDownstream neighbor of SON. (430 aa)    
Predicted Functional Partners:
ORC1
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
   
  
 0.878
MCM2
DNA helicase; Belongs to the MCM family.
   
   0.846
POLD2
DNA polymerase delta 2, accessory subunit.
   
 
 0.840
G1P4R7_MYOLU
Uncharacterized protein.
   
 
 0.835
MRPS6
Mitochondrial ribosomal protein S6.
      
 0.816
GART
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
   
  
 0.797
RFC4
Replication factor C subunit 4.
   
  
 0.795
C18orf54
Chromosome 18 open reading frame 54.
      
 0.769
C3orf14
Chromosome 3 open reading frame 14.
      
 0.769
MCM9
Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family.
   
   0.755
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.