STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DROSHADrosha ribonuclease III. (1378 aa)    
Predicted Functional Partners:
DGCR8
DGCR8 microprocessor complex subunit.
   
 0.999
DDX5
DEAD-box helicase 5; Belongs to the DEAD box helicase family.
  
 0.986
TARBP2
RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...]
    
 0.963
MRPS9
Mitochondrial ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
   
 
 0.956
MRPL27
Mitochondrial ribosomal protein L27.
  
 
 0.955
AGO1
Argonaute RISC component 1.
    
 0.951
AGO2
Argonaute RISC catalytic component 2.
    
 0.948
MRPL19
Mitochondrial ribosomal protein L19.
  
 
 0.946
MRPL17
Mitochondrial ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family.
   
 
 0.944
DDX17
DEAD-box helicase 17; Belongs to the DEAD box helicase family.
  
 0.944
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.