| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| F2 | F5 | ENSMLUP00000016081 | ENSMLUP00000007764 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Coagulation factor V; Belongs to the multicopper oxidase family. | 0.998 |
| F2 | F8 | ENSMLUP00000016081 | ENSMLUP00000001932 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Coagulation factor VIII; Belongs to the multicopper oxidase family. | 0.960 |
| F2 | FGA | ENSMLUP00000016081 | ENSMLUP00000005057 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Fibrinogen alpha chain. | 0.999 |
| F2 | FGB | ENSMLUP00000016081 | ENSMLUP00000007026 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Fibrinogen beta chain. | 0.999 |
| F2 | PLAT | ENSMLUP00000016081 | ENSMLUP00000001832 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Plasminogen activator; Belongs to the peptidase S1 family. | 0.520 |
| F2 | PLAU | ENSMLUP00000016081 | ENSMLUP00000011653 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Plasminogen activator, urokinase. | 0.452 |
| F2 | PLAUR | ENSMLUP00000016081 | ENSMLUP00000008853 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Plasminogen activator, urokinase receptor. | 0.615 |
| F2 | SERPINE1 | ENSMLUP00000016081 | ENSMLUP00000000920 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Serpin family E member 1; Belongs to the serpin family. | 0.602 |
| F2 | SERPINE2 | ENSMLUP00000016081 | ENSMLUP00000002384 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Serpin family E member 2; Belongs to the serpin family. | 0.997 |
| F2 | VTN | ENSMLUP00000016081 | ENSMLUP00000011216 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | SMB domain-containing protein. | 0.740 |
| F5 | F2 | ENSMLUP00000007764 | ENSMLUP00000016081 | Coagulation factor V; Belongs to the multicopper oxidase family. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.998 |
| F5 | F8 | ENSMLUP00000007764 | ENSMLUP00000001932 | Coagulation factor V; Belongs to the multicopper oxidase family. | Coagulation factor VIII; Belongs to the multicopper oxidase family. | 0.960 |
| F5 | FGA | ENSMLUP00000007764 | ENSMLUP00000005057 | Coagulation factor V; Belongs to the multicopper oxidase family. | Fibrinogen alpha chain. | 0.703 |
| F5 | FGB | ENSMLUP00000007764 | ENSMLUP00000007026 | Coagulation factor V; Belongs to the multicopper oxidase family. | Fibrinogen beta chain. | 0.780 |
| F5 | PLAT | ENSMLUP00000007764 | ENSMLUP00000001832 | Coagulation factor V; Belongs to the multicopper oxidase family. | Plasminogen activator; Belongs to the peptidase S1 family. | 0.531 |
| F5 | PLAU | ENSMLUP00000007764 | ENSMLUP00000011653 | Coagulation factor V; Belongs to the multicopper oxidase family. | Plasminogen activator, urokinase. | 0.522 |
| F5 | SERPINE1 | ENSMLUP00000007764 | ENSMLUP00000000920 | Coagulation factor V; Belongs to the multicopper oxidase family. | Serpin family E member 1; Belongs to the serpin family. | 0.509 |
| F5 | SERPINE2 | ENSMLUP00000007764 | ENSMLUP00000002384 | Coagulation factor V; Belongs to the multicopper oxidase family. | Serpin family E member 2; Belongs to the serpin family. | 0.959 |
| F8 | F2 | ENSMLUP00000001932 | ENSMLUP00000016081 | Coagulation factor VIII; Belongs to the multicopper oxidase family. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.960 |
| F8 | F5 | ENSMLUP00000001932 | ENSMLUP00000007764 | Coagulation factor VIII; Belongs to the multicopper oxidase family. | Coagulation factor V; Belongs to the multicopper oxidase family. | 0.960 |