STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDE6DRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...] (133 aa)    
Predicted Functional Partners:
ARL3
ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family.
   
 0.986
KRAS
KRAS proto-oncogene, GTPase.
    
 0.982
ARL13B
ADP ribosylation factor like GTPase 13B.
     
 0.979
G1QE38_MYOLU
Uncharacterized protein.
    
 
 0.978
ARL2
Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.
    
 0.971
G1Q2G0_MYOLU
Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.
    
 0.971
GUCY1B1
Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
    
 0.954
G1PXE4_MYOLU
Uncharacterized protein.
    
 0.940
RHEB
Ras homolog, mTORC1 binding.
    
 0.916
RHEBL1
RHEB like 1.
    
 0.916
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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