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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UNC13CUnc-13 homolog C. (2214 aa)    
Predicted Functional Partners:
RIMS2
Regulating synaptic membrane exocytosis 2.
    
0.999
UNC13B
Unc-13 homolog B.
  
  
 
0.874
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
 
 0.869
RIMS3
Regulating synaptic membrane exocytosis 3.
    
 0.865
RIMS1
Regulating synaptic membrane exocytosis 1.
    
 0.865
RIMS4
Regulating synaptic membrane exocytosis 4.
    
 0.837
STXBP1
Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family.
    
 0.835
SNAP25
Synaptosomal-associated protein; Belongs to the SNAP-25 family.
   
 0.800
TSPOAP1
TSPO associated protein 1.
   
 0.787
STXBP3
Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family.
    
 0.779
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.