STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PREX2Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2. (1561 aa)    
Predicted Functional Partners:
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
     
 0.984
CDC42
Cell division cycle 42.
    
 0.921
GNB3
G protein subunit beta 3.
    
 0.884
GNB5
G protein subunit beta 5.
    
 0.884
RAC1
Rac family small GTPase 1.
    
 0.851
RAC2
Rac family small GTPase 2.
    
 0.851
GNB1
G protein subunit beta 1.
    
 0.847
GNB2
G protein subunit beta 2.
    
 0.847
GNB4
G protein subunit beta 4.
    
 0.847
RHOG
Ras homolog family member G.
    
 0.844
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.