ANKRD28 protein (Myotis lucifugus) - STRING interaction network

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Score

ANKRD28

Ankyrin repeat domain 28. (1088 aa)

Predicted Functional Partners:

PPP6R3

0.989

PPP6C

0.989

PPP6R2

0.909

BRCA1

0.692

IFT81

0.691

LRCH3

0.682

LOC102423130

0.669

COPS5

0.663

CUL5

0.661

IFT22

0.659

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD28	BRCA1	ENSMLUP00000002545	ENSMLUP00000003770	Ankyrin repeat domain 28.	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	0.692
ANKRD28	COPS5	ENSMLUP00000002545	ENSMLUP00000010651	Ankyrin repeat domain 28.	COP9 signalosome subunit 5.	0.663
ANKRD28	CUL5	ENSMLUP00000002545	ENSMLUP00000010755	Ankyrin repeat domain 28.	Cullin 5; Belongs to the cullin family.	0.661
ANKRD28	IFT22	ENSMLUP00000002545	ENSMLUP00000011499	Ankyrin repeat domain 28.	Intraflagellar transport 22.	0.659
ANKRD28	IFT81	ENSMLUP00000002545	ENSMLUP00000001555	Ankyrin repeat domain 28.	Intraflagellar transport 81.	0.691
ANKRD28	LOC102423130	ENSMLUP00000002545	ENSMLUP00000020170	Ankyrin repeat domain 28.	Ubiquitin-like domain-containing protein.	0.669
ANKRD28	LRCH3	ENSMLUP00000002545	ENSMLUP00000009771	Ankyrin repeat domain 28.	Leucine rich repeats and calponin homology domain containing 3.	0.682
ANKRD28	PPP6C	ENSMLUP00000002545	ENSMLUP00000019512	Ankyrin repeat domain 28.	Serine/threonine-protein phosphatase.	0.989
ANKRD28	PPP6R2	ENSMLUP00000002545	ENSMLUP00000014567	Ankyrin repeat domain 28.	Protein phosphatase 6 regulatory subunit 2.	0.909
ANKRD28	PPP6R3	ENSMLUP00000002545	ENSMLUP00000011944	Ankyrin repeat domain 28.	Protein phosphatase 6 regulatory subunit 3.	0.989
BRCA1	ANKRD28	ENSMLUP00000003770	ENSMLUP00000002545	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	Ankyrin repeat domain 28.	0.692
BRCA1	COPS5	ENSMLUP00000003770	ENSMLUP00000010651	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	COP9 signalosome subunit 5.	0.612
BRCA1	LOC102423130	ENSMLUP00000003770	ENSMLUP00000020170	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	Ubiquitin-like domain-containing protein.	0.541
COPS5	ANKRD28	ENSMLUP00000010651	ENSMLUP00000002545	COP9 signalosome subunit 5.	Ankyrin repeat domain 28.	0.663
COPS5	BRCA1	ENSMLUP00000010651	ENSMLUP00000003770	COP9 signalosome subunit 5.	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	0.612
COPS5	CUL5	ENSMLUP00000010651	ENSMLUP00000010755	COP9 signalosome subunit 5.	Cullin 5; Belongs to the cullin family.	0.876
COPS5	LOC102423130	ENSMLUP00000010651	ENSMLUP00000020170	COP9 signalosome subunit 5.	Ubiquitin-like domain-containing protein.	0.993
CUL5	ANKRD28	ENSMLUP00000010755	ENSMLUP00000002545	Cullin 5; Belongs to the cullin family.	Ankyrin repeat domain 28.	0.661
CUL5	COPS5	ENSMLUP00000010755	ENSMLUP00000010651	Cullin 5; Belongs to the cullin family.	COP9 signalosome subunit 5.	0.876
CUL5	LOC102423130	ENSMLUP00000010755	ENSMLUP00000020170	Cullin 5; Belongs to the cullin family.	Ubiquitin-like domain-containing protein.	0.992