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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (462 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
   
 0.997
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.985
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.985
RAC1
Rac family small GTPase 1.
   
 0.984
PAK1
Non-specific serine/threonine protein kinase.
  
 
0.971
ITSN2
Intersectin 2.
    
 0.964
NCK1
Cytoplasmic protein.
    
 0.958
TTN
Titin.
    
 0.957
MYLK
Myosin light chain kinase.
    
0.957
RAC2
Rac family small GTPase 2.
   
 0.956
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.