STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VPS35LVPS35 endosomal protein sorting factor like. (962 aa)    
Predicted Functional Partners:
CCDC22
Coiled-coil domain containing 22.
    
 
 0.965
PLK1
Serine/threonine-protein kinase PLK.
   
 
  0.954
COMMD6
COMM domain containing 6.
    
 
 0.948
VPS29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
    
 
 0.940
CCDC93
Coiled-coil domain containing 93.
    
 
 0.917
COMMD2
COMM domain containing 2.
    
 
 0.871
VPS26C
Uncharacterized protein.
   
 
 0.866
ENSMLUP00000018188
annotation not available
   
 
 0.866
COMMD4
COMM domain containing 4.
    
 
 0.853
COMMD10
COMM domain containing 10.
    
 
 0.849
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.