STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IKZF1IKAROS family zinc finger 1. (465 aa)    
Predicted Functional Partners:
CRBN
Cereblon.
    
 
 0.989
DDB1
Damage specific DNA binding protein 1.
    
 0.957
IKZF3
IKAROS family zinc finger 3.
   
 
0.883
CHD4
Uncharacterized protein.
   
 0.821
RUNX1
Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
   
 0.785
G1PBB6_MYOLU
Uncharacterized protein.
    
  0.763
IKZF4
IKAROS family zinc finger 4.
   
  
0.760
IKZF5
IKAROS family zinc finger 5.
    
 
0.747
RAD21
RAD21 cohesin complex component.
    
 0.715
IRF4
Interferon regulatory factor 4.
   
 
 0.711
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.