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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD14CD14 molecule. (365 aa)    
Predicted Functional Partners:
TLR4
Toll like receptor 4; Belongs to the Toll-like receptor family.
   
 0.985
LY96
Lymphocyte antigen 96.
   
 
 0.974
TLR2
Toll-like receptor.
   
0.960
PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
     
 0.958
TLR6
Toll like receptor 6; Belongs to the Toll-like receptor family.
   
 0.859
BPI
Bactericidal permeability increasing protein.
    
 0.852
LBP
Lipopolysaccharide binding protein.
    
 0.852
G1Q3Z1_MYOLU
Uncharacterized protein.
    
 0.852
TYROBP
TYRO protein tyrosine kinase binding protein.
   
    0.798
TLR8
Toll like receptor 8; Belongs to the Toll-like receptor family.
   
 0.782
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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