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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMCO6Transmembrane and coiled-coil domains 6. (493 aa)    
Predicted Functional Partners:
KPNB1
Karyopherin subunit beta 1.
   
 0.912
CSE1L
Chromosome segregation 1 like.
   
 0.888
NUP153
Nucleoporin 153.
   
 
 0.778
NCBP1
Nuclear cap binding protein subunit 1.
   
 
 0.771
ZNF511
Zinc finger protein 511.
    
   0.746
ALS2
Alsin Rho guanine nucleotide exchange factor ALS2.
   
 
 0.740
EXOSC10
Exosome component 10.
    
 
 0.739
RRP8
Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...]
    
   0.739
RANBP2
RAN binding protein 2.
   
 
 0.719
GCC2
GRIP and coiled-coil domain containing 2.
   
 
 0.690
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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