STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)    
Predicted Functional Partners:
WAS
WASP actin nucleation promoting factor.
   
 
 0.881
ARHGAP30
Rho GTPase activating protein 30.
   
  
 0.847
TYROBP
TYRO protein tyrosine kinase binding protein.
   
  
 0.841
ARHGAP4
Rho GTPase activating protein 4.
   
  
 0.825
LAPTM5
Lysosomal protein transmembrane 5.
   
  
 0.821
DHFR
DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.
    
 0.816
ITGB2
Integrin beta.
   
  
 0.810
FPGS
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
    
 0.808
CFL2
Cofilin 2; Belongs to the actin-binding proteins ADF family.
   
 0.804
DUT
Deoxyuridine triphosphatase.
      0.795
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.