STAM2 protein (Myotis lucifugus) - STRING interaction network

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Score

STAM2

Signal transducing adaptor molecule 2. (533 aa)

Predicted Functional Partners:

HGS

0.999

STAMBP

0.993

USP8

0.989

STAM

0.979

PTPN23

0.978

ITSN2

0.970

ITSN1

0.970

TSG101

0.969

STAMBPL1

0.959

JAK3

0.946

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HGS	ITSN1	ENSMLUP00000017883	ENSMLUP00000016474	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Intersectin 1.	0.876
HGS	ITSN2	ENSMLUP00000017883	ENSMLUP00000002296	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Intersectin 2.	0.970
HGS	PTPN23	ENSMLUP00000017883	ENSMLUP00000014180	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Protein tyrosine phosphatase non-receptor type 23.	0.871
HGS	STAM	ENSMLUP00000017883	ENSMLUP00000015970	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Signal transducing adaptor molecule.	0.999
HGS	STAM2	ENSMLUP00000017883	ENSMLUP00000003166	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Signal transducing adaptor molecule 2.	0.999
HGS	TSG101	ENSMLUP00000017883	ENSMLUP00000014905	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Tumor susceptibility 101.	0.998
HGS	USP8	ENSMLUP00000017883	ENSMLUP00000000359	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.	0.981
ITSN1	HGS	ENSMLUP00000016474	ENSMLUP00000017883	Intersectin 1.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	0.876
ITSN1	ITSN2	ENSMLUP00000016474	ENSMLUP00000002296	Intersectin 1.	Intersectin 2.	0.975
ITSN1	JAK3	ENSMLUP00000016474	ENSMLUP00000006103	Intersectin 1.	Tyrosine-protein kinase.	0.603
ITSN1	PTPN23	ENSMLUP00000016474	ENSMLUP00000014180	Intersectin 1.	Protein tyrosine phosphatase non-receptor type 23.	0.487
ITSN1	STAM	ENSMLUP00000016474	ENSMLUP00000015970	Intersectin 1.	Signal transducing adaptor molecule.	0.970
ITSN1	STAM2	ENSMLUP00000016474	ENSMLUP00000003166	Intersectin 1.	Signal transducing adaptor molecule 2.	0.970
ITSN2	HGS	ENSMLUP00000002296	ENSMLUP00000017883	Intersectin 2.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	0.970
ITSN2	ITSN1	ENSMLUP00000002296	ENSMLUP00000016474	Intersectin 2.	Intersectin 1.	0.975
ITSN2	JAK3	ENSMLUP00000002296	ENSMLUP00000006103	Intersectin 2.	Tyrosine-protein kinase.	0.724
ITSN2	PTPN23	ENSMLUP00000002296	ENSMLUP00000014180	Intersectin 2.	Protein tyrosine phosphatase non-receptor type 23.	0.573
ITSN2	STAM	ENSMLUP00000002296	ENSMLUP00000015970	Intersectin 2.	Signal transducing adaptor molecule.	0.970
ITSN2	STAM2	ENSMLUP00000002296	ENSMLUP00000003166	Intersectin 2.	Signal transducing adaptor molecule 2.	0.970
JAK3	ITSN1	ENSMLUP00000006103	ENSMLUP00000016474	Tyrosine-protein kinase.	Intersectin 1.	0.603