STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MLH1MutL homolog 1. (755 aa)    
Predicted Functional Partners:
PMS2
PMS1 homolog 2, mismatch repair system component.
  
 
0.999
MSH6
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 0.999
MSH2
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 0.999
MLH3
MutL homolog 3.
    
0.998
MSH3
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 0.995
PMS1
PMS1 homolog 1, mismatch repair system component.
  
 
0.995
BLM
BLM RecQ like helicase.
  
 0.993
BRIP1
BRCA1 interacting protein C-terminal helicase 1.
   
 0.989
RTEL1
Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]
   
 0.989
L7N119_MYOLU
Uncharacterized protein.
   
 0.988
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.