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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHF6PHD finger protein 6. (365 aa)    
Predicted Functional Partners:
RBBP4
RB binding protein 4, chromatin remodeling factor.
   
 0.939
RBBP7
RB binding protein 7, chromatin remodeling factor.
   
 0.894
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
    
 0.890
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
   
 0.856
SUZ12
SUZ12 polycomb repressive complex 2 subunit.
   
 0.844
EED
Embryonic ectoderm development.
   
 0.835
RUNX1
Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
   
 0.834
PHF1
PHD finger protein 1.
   
 0.802
KDM6A
Lysine demethylase 6A.
  
 0.794
MPHOSPH8
M-phase phosphoprotein 8.
    
 0.791
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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