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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PMS2PMS1 homolog 2, mismatch repair system component. (855 aa)    
Predicted Functional Partners:
MLH1
MutL homolog 1.
  
 
0.999
MSH2
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 0.999
MSH6
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
 0.998
MSH3
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 0.990
G1PM15_MYOLU
DNA_MISMATCH_REPAIR_2 domain-containing protein.
  
 0.973
L7N119_MYOLU
Uncharacterized protein.
   
 0.971
LOC102429896
XPGI domain-containing protein.
   
 0.971
MSH4
MutS homolog 4.
 
 0.967
BRIP1
BRCA1 interacting protein C-terminal helicase 1.
   
 0.960
RTEL1
Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]
   
 0.960
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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