| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EGF | IGF1 | ENSMLUP00000014120 | ENSMLUP00000010317 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Insulin like growth factor 1. | 0.967 |
| EGF | IGF1R | ENSMLUP00000014120 | ENSMLUP00000015675 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Tyrosine-protein kinase receptor. | 0.937 |
| EGF | INS | ENSMLUP00000014120 | ENSMLUP00000003521 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.969 |
| EGF | INSR | ENSMLUP00000014120 | ENSMLUP00000012576 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Tyrosine-protein kinase receptor. | 0.910 |
| EGF | INSRR | ENSMLUP00000014120 | ENSMLUP00000009532 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Tyrosine-protein kinase receptor. | 0.906 |
| EGF | P4HB | ENSMLUP00000014120 | ENSMLUP00000017209 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Protein disulfide-isomerase. | 0.480 |
| GHRL | IGF1 | ENSMLUP00000010938 | ENSMLUP00000010317 | Ghrelin and obestatin prepropeptide. | Insulin like growth factor 1. | 0.980 |
| GHRL | INS | ENSMLUP00000010938 | ENSMLUP00000003521 | Ghrelin and obestatin prepropeptide. | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.988 |
| GHRL | SST | ENSMLUP00000010938 | ENSMLUP00000011737 | Ghrelin and obestatin prepropeptide. | Somatostatin. | 0.769 |
| IDE | INS | ENSMLUP00000008690 | ENSMLUP00000003521 | Insulin degrading enzyme; Belongs to the peptidase M16 family. | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.998 |
| IGF1 | EGF | ENSMLUP00000010317 | ENSMLUP00000014120 | Insulin like growth factor 1. | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | 0.967 |
| IGF1 | GHRL | ENSMLUP00000010317 | ENSMLUP00000010938 | Insulin like growth factor 1. | Ghrelin and obestatin prepropeptide. | 0.980 |
| IGF1 | IGF1R | ENSMLUP00000010317 | ENSMLUP00000015675 | Insulin like growth factor 1. | Tyrosine-protein kinase receptor. | 0.999 |
| IGF1 | INS | ENSMLUP00000010317 | ENSMLUP00000003521 | Insulin like growth factor 1. | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.974 |
| IGF1 | INSR | ENSMLUP00000010317 | ENSMLUP00000012576 | Insulin like growth factor 1. | Tyrosine-protein kinase receptor. | 0.998 |
| IGF1 | INSRR | ENSMLUP00000010317 | ENSMLUP00000009532 | Insulin like growth factor 1. | Tyrosine-protein kinase receptor. | 0.977 |
| IGF1 | IRS1 | ENSMLUP00000010317 | ENSMLUP00000019635 | Insulin like growth factor 1. | Insulin receptor substrate 1. | 0.877 |
| IGF1 | SST | ENSMLUP00000010317 | ENSMLUP00000011737 | Insulin like growth factor 1. | Somatostatin. | 0.591 |
| IGF1R | EGF | ENSMLUP00000015675 | ENSMLUP00000014120 | Tyrosine-protein kinase receptor. | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | 0.937 |
| IGF1R | IGF1 | ENSMLUP00000015675 | ENSMLUP00000010317 | Tyrosine-protein kinase receptor. | Insulin like growth factor 1. | 0.999 |