INS protein (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGF	G1P5B5_MYOLU	ENSMLUP00000014120	ENSMLUP00000005193	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Uncharacterized protein.	0.999
EGF	IGF1	ENSMLUP00000014120	ENSMLUP00000010317	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Insulin like growth factor 1.	0.967
EGF	IGF1R	ENSMLUP00000014120	ENSMLUP00000015675	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Tyrosine-protein kinase receptor.	0.975
EGF	INS	ENSMLUP00000014120	ENSMLUP00000003521	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.990
EGF	INSR	ENSMLUP00000014120	ENSMLUP00000012576	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Tyrosine-protein kinase receptor.	0.977
EGF	INSRR	ENSMLUP00000014120	ENSMLUP00000009532	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Tyrosine-protein kinase receptor.	0.878
G1P5B5_MYOLU	EGF	ENSMLUP00000005193	ENSMLUP00000014120	Uncharacterized protein.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.999
G1P5B5_MYOLU	IGF1	ENSMLUP00000005193	ENSMLUP00000010317	Uncharacterized protein.	Insulin like growth factor 1.	0.953
G1P5B5_MYOLU	IGF1R	ENSMLUP00000005193	ENSMLUP00000015675	Uncharacterized protein.	Tyrosine-protein kinase receptor.	0.949
G1P5B5_MYOLU	INS	ENSMLUP00000005193	ENSMLUP00000003521	Uncharacterized protein.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.978
G1P5B5_MYOLU	INSR	ENSMLUP00000005193	ENSMLUP00000012576	Uncharacterized protein.	Tyrosine-protein kinase receptor.	0.722
G1P5B5_MYOLU	INSRR	ENSMLUP00000005193	ENSMLUP00000009532	Uncharacterized protein.	Tyrosine-protein kinase receptor.	0.715
G1P5B5_MYOLU	IRS1	ENSMLUP00000005193	ENSMLUP00000019635	Uncharacterized protein.	Insulin receptor substrate 1.	0.840
G1P5B5_MYOLU	IRS4	ENSMLUP00000005193	ENSMLUP00000009770	Uncharacterized protein.	Insulin receptor substrate 4.	0.522
GHRL	IGF1	ENSMLUP00000010938	ENSMLUP00000010317	Ghrelin and obestatin prepropeptide.	Insulin like growth factor 1.	0.966
GHRL	INS	ENSMLUP00000010938	ENSMLUP00000003521	Ghrelin and obestatin prepropeptide.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.978
IDE	IGF1	ENSMLUP00000008690	ENSMLUP00000010317	Insulin degrading enzyme; Belongs to the peptidase M16 family.	Insulin like growth factor 1.	0.410
IDE	INS	ENSMLUP00000008690	ENSMLUP00000003521	Insulin degrading enzyme; Belongs to the peptidase M16 family.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.996
IDE	INSR	ENSMLUP00000008690	ENSMLUP00000012576	Insulin degrading enzyme; Belongs to the peptidase M16 family.	Tyrosine-protein kinase receptor.	0.492
IGF1	EGF	ENSMLUP00000010317	ENSMLUP00000014120	Insulin like growth factor 1.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.967