NFE2L2 protein (Myotis lucifugus) - STRING interaction network

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

NFE2L2

Nuclear factor, erythroid 2 like 2. (603 aa)

Predicted Functional Partners:

KEAP1

0.999

GSK3B

0.987

KLHL18

0.978

EP300

0.977

MAFF

0.954

DDIT3

0.940

MAFB

0.934

CUL3

0.932

PARK7

0.927

EIF2AK3

0.925

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUL3	GSK3B	ENSMLUP00000007405	ENSMLUP00000002622	Cullin 3; Belongs to the cullin family.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.747
CUL3	KEAP1	ENSMLUP00000007405	ENSMLUP00000013790	Cullin 3; Belongs to the cullin family.	Kelch like ECH associated protein 1.	0.999
CUL3	KLHL18	ENSMLUP00000007405	ENSMLUP00000014157	Cullin 3; Belongs to the cullin family.	Kelch like family member 18.	0.971
CUL3	MAFB	ENSMLUP00000007405	ENSMLUP00000002748	Cullin 3; Belongs to the cullin family.	MAF bZIP transcription factor B.	0.742
CUL3	MAFF	ENSMLUP00000007405	ENSMLUP00000010342	Cullin 3; Belongs to the cullin family.	MAF bZIP transcription factor F.	0.625
CUL3	NFE2L2	ENSMLUP00000007405	ENSMLUP00000003561	Cullin 3; Belongs to the cullin family.	Nuclear factor, erythroid 2 like 2.	0.932
DDIT3	EIF2AK3	ENSMLUP00000000958	ENSMLUP00000009798	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	Eukaryotic translation initiation factor 2 alpha kinase 3.	0.459
DDIT3	EP300	ENSMLUP00000000958	ENSMLUP00000013493	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	E1A binding protein p300.	0.488
DDIT3	NFE2L2	ENSMLUP00000000958	ENSMLUP00000003561	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	Nuclear factor, erythroid 2 like 2.	0.940
EIF2AK3	DDIT3	ENSMLUP00000009798	ENSMLUP00000000958	Eukaryotic translation initiation factor 2 alpha kinase 3.	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	0.459
EIF2AK3	NFE2L2	ENSMLUP00000009798	ENSMLUP00000003561	Eukaryotic translation initiation factor 2 alpha kinase 3.	Nuclear factor, erythroid 2 like 2.	0.925
EP300	DDIT3	ENSMLUP00000013493	ENSMLUP00000000958	E1A binding protein p300.	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	0.488
EP300	NFE2L2	ENSMLUP00000013493	ENSMLUP00000003561	E1A binding protein p300.	Nuclear factor, erythroid 2 like 2.	0.977
GSK3B	CUL3	ENSMLUP00000002622	ENSMLUP00000007405	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	Cullin 3; Belongs to the cullin family.	0.747
GSK3B	KEAP1	ENSMLUP00000002622	ENSMLUP00000013790	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	Kelch like ECH associated protein 1.	0.600
GSK3B	NFE2L2	ENSMLUP00000002622	ENSMLUP00000003561	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	Nuclear factor, erythroid 2 like 2.	0.987
KEAP1	CUL3	ENSMLUP00000013790	ENSMLUP00000007405	Kelch like ECH associated protein 1.	Cullin 3; Belongs to the cullin family.	0.999
KEAP1	GSK3B	ENSMLUP00000013790	ENSMLUP00000002622	Kelch like ECH associated protein 1.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.600
KEAP1	MAFB	ENSMLUP00000013790	ENSMLUP00000002748	Kelch like ECH associated protein 1.	MAF bZIP transcription factor B.	0.571
KEAP1	MAFF	ENSMLUP00000013790	ENSMLUP00000010342	Kelch like ECH associated protein 1.	MAF bZIP transcription factor F.	0.571