Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TREM1Ig-like domain-containing protein. (233 aa)    
Predicted Functional Partners:
TYROBP
TYRO protein tyrosine kinase binding protein.
   
 0.980
TREM2
Triggering receptor expressed on myeloid cells 2.
     
 0.910
TREML1
Triggering receptor expressed on myeloid cells like 1.
   
 
 0.780
TNFRSF1A
TNF receptor superfamily member 1A.
   
  
 0.702
IL1B
Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.
   
  
 0.666
G1NZQ0_MYOLU
IG domain-containing protein.
   
 
 0.655
G1QE92_MYOLU
IGv domain-containing protein.
   
 
 0.655
G1P2N1_MYOLU
Ig-like domain-containing protein.
   
 
 0.638
L7N1P8_MYOLU
Ig-like domain-containing protein.
   
 
 0.611
G1Q9H5_MYOLU
IG domain-containing protein.
   
 
 0.611
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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