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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPTLC1Serine palmitoyltransferase long chain base subunit 1. (476 aa)    
Predicted Functional Partners:
SPTLC3
Serine palmitoyltransferase long chain base subunit 3.
  
0.998
SPTLC2
Serine palmitoyltransferase long chain base subunit 2.
  
0.998
SPTSSB
Serine palmitoyltransferase small subunit B.
    
 0.986
SPTSSA
Serine palmitoyltransferase small subunit A.
    
 0.983
ISM1
Isthmin 1.
 
 
 0.977
G1P476_MYOLU
AMOP domain-containing protein.
 
 
 0.977
ORMDL3
ORM1-like protein; Negative regulator of sphingolipid synthesis.
    
 0.975
ORMDL1
ORM1-like protein; Negative regulator of sphingolipid synthesis.
    
 
 0.965
KDSR
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.958
ORMDL2
ORM1-like protein; Negative regulator of sphingolipid synthesis.
    
 
 0.958
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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