STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PELI3E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (444 aa)    
Predicted Functional Partners:
IRAK1
Interleukin 1 receptor associated kinase 1.
    
 0.959
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.941
IRAK4
Interleukin 1 receptor associated kinase 4.
    
 0.892
UBE2V1
Ubiquitin conjugating enzyme E2 V1.
    
 0.887
IRAK2
Interleukin 1 receptor associated kinase 2.
    
 0.865
G1PEX8_MYOLU
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.797
RIPK1
Receptor interacting serine/threonine kinase 1.
    
 0.769
MAP3K7
Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    
 0.763
IQCC
IQ motif containing C.
      
 0.749
G1Q9C7_MYOLU
Uncharacterized protein.
      
 0.749
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.