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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCAPSREBF chaperone. (1280 aa)    
Predicted Functional Partners:
SREBF2
Sterol regulatory element binding transcription factor 2.
   
 0.999
INSIG1
Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.
   
 0.961
INSIG2
Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis.
   
 0.961
NPC2
NPC intracellular cholesterol transporter 2.
   
 0.940
G1Q6J7_MYOLU
BHLH domain-containing protein.
   
 0.924
MBTPS1
Membrane bound transcription factor peptidase, site 1.
   
 
 0.804
G1PV07_MYOLU
PKS_AT domain-containing protein.
   
  
 0.615
SCD
Stearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family.
   
  
 0.573
OSBPL10
Oxysterol-binding protein; Belongs to the OSBP family.
   
 0.567
OSBPL8
Oxysterol-binding protein; Belongs to the OSBP family.
   
 0.567
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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