Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFPAlpha fetoprotein. (609 aa)    
Predicted Functional Partners:
G1Q092_MYOLU
Uncharacterized protein.
     
0.901
AHSG
Alpha 2-HS glycoprotein.
   
 0.881
PLG
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
   
 0.840
FAM20C
FAM20C golgi associated secretory pathway kinase.
    
  0.805
HPX
Hemopexin.
   
 0.772
LOC102441084
SERPIN domain-containing protein; Belongs to the serpin family.
   
 0.769
SOX17
SRY-box transcription factor 17.
      
 0.759
FGA
Fibrinogen alpha chain.
   
 0.756
HNF4A
Hepatocyte nuclear factor 4 alpha.
   
 
 0.753
TNF
Tumor necrosis factor; Belongs to the tumor necrosis factor family.
    
 
 0.753
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
Server load: low (12%) [HD]