PROCR protein (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PROCR

Protein C receptor. (241 aa)

Predicted Functional Partners:

THBD

0.968

VSIR

0.890

F2

0.861

PROS1

0.753

PRTN3

0.741

F7

0.733

ELANE

0.719

PLAT

0.700

L7N1Q3_MYOLU

0.668

G1Q5N3_MYOLU

0.668

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ELANE	F2	ENSMLUP00000009669	ENSMLUP00000016081	Elastase, neutrophil expressed; Belongs to the peptidase S1 family.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.962
ELANE	PROCR	ENSMLUP00000009669	ENSMLUP00000004063	Elastase, neutrophil expressed; Belongs to the peptidase S1 family.	Protein C receptor.	0.719
ELANE	PRTN3	ENSMLUP00000009669	ENSMLUP00000005046	Elastase, neutrophil expressed; Belongs to the peptidase S1 family.	Proteinase 3; Belongs to the peptidase S1 family.	0.543
ELANE	THBD	ENSMLUP00000009669	ENSMLUP00000017309	Elastase, neutrophil expressed; Belongs to the peptidase S1 family.	Thrombomodulin.	0.569
F2	ELANE	ENSMLUP00000016081	ENSMLUP00000009669	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Elastase, neutrophil expressed; Belongs to the peptidase S1 family.	0.962
F2	F7	ENSMLUP00000016081	ENSMLUP00000012711	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor VII.	0.902
F2	G1Q5N3_MYOLU	ENSMLUP00000016081	ENSMLUP00000019016	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.994
F2	L7N1Q3_MYOLU	ENSMLUP00000016081	ENSMLUP00000012776	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.994
F2	PLAT	ENSMLUP00000016081	ENSMLUP00000001832	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Plasminogen activator; Belongs to the peptidase S1 family.	0.520
F2	PROCR	ENSMLUP00000016081	ENSMLUP00000004063	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Protein C receptor.	0.861
F2	PROS1	ENSMLUP00000016081	ENSMLUP00000015928	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Protein S.	0.454
F2	PRTN3	ENSMLUP00000016081	ENSMLUP00000005046	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Proteinase 3; Belongs to the peptidase S1 family.	0.660
F2	THBD	ENSMLUP00000016081	ENSMLUP00000017309	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Thrombomodulin.	0.998
F7	F2	ENSMLUP00000012711	ENSMLUP00000016081	Coagulation factor VII.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.902
F7	G1Q5N3_MYOLU	ENSMLUP00000012711	ENSMLUP00000019016	Coagulation factor VII.	Uncharacterized protein.	0.939
F7	L7N1Q3_MYOLU	ENSMLUP00000012711	ENSMLUP00000012776	Coagulation factor VII.	Uncharacterized protein.	0.939
F7	PROCR	ENSMLUP00000012711	ENSMLUP00000004063	Coagulation factor VII.	Protein C receptor.	0.733
F7	PROS1	ENSMLUP00000012711	ENSMLUP00000015928	Coagulation factor VII.	Protein S.	0.559
F7	THBD	ENSMLUP00000012711	ENSMLUP00000017309	Coagulation factor VII.	Thrombomodulin.	0.847
G1Q5N3_MYOLU	F2	ENSMLUP00000019016	ENSMLUP00000016081	Uncharacterized protein.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.994