STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPC2NPC intracellular cholesterol transporter 2. (188 aa)    
Predicted Functional Partners:
NPC1
NPC intracellular cholesterol transporter 1.
   
 0.998
NPC1L1
NPC1 like intracellular cholesterol transporter 1.
   
 0.981
SCAP
SREBF chaperone.
   
 0.940
APOB
Apolipoprotein B.
     
 0.806
G1PRU9_MYOLU
Uncharacterized protein.
      
 0.674
GM2A
GM2 ganglioside activator.
   
  
 0.660
ATP7B
ATPase copper transporting beta.
      
 0.628
NUDT19
Nudix hydrolase 19.
    
   0.615
SMPDL3A
Acid sphingomyelinase-like phosphodiesterase.
   
 
  0.604
PTCHD4
Patched domain containing 4.
   
 
  0.594
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.